简介
外科学博士，旅美学者，美国加州大学胸心外科学博士后，主任医生，胸外科特殊专家，广西知名医学专家，外科学博士研究生导师，广西医科大学临床医学III级教授，《Inflammation Research》等SCI杂志特约审稿专家。曾分别在美国洛杉矶加州大学（University of California, Los Angeles)、全美国心胸外科临床排名第一的克利夫兰医学中心(Cleveland Clinic)开展博士后研究及进行临床心胸血管外科医师训练。先后主持完成国家自然科学基金，广西科技创新项目，广西自然科学基金，广西卫生厅重点研究项目等10余项科研课题，发表SCI论文近30篇。创新性设计出“循证医学临床网络诊断及教学平台”并应用于临床实践，获得广西第七届教育教学软件大赛一等奖、广西第七届教育教学软件大赛最佳教学设计奖、全国第九届多媒体课件大赛二等奖（排名第一）。 近年文章举例：1.Xu Z, Qin F, Yuan L, Wei J, Sun Y, Qin J, Deng K, Zheng T, Li S*. EGFR DNA Methylation Correlates With EGFR Expression, Immune Cell Infiltration, and Overall Survival in Lung Adenocarcinoma. Front Oncol. 2021 Aug 10;11:691915. doi: 10.3389/fonc.2021.691915. PMID: 34447695; PMCID: PMC8383738.2.Qin J, Xu Z, Deng K, Qin F, Wei J, Yuan L, Sun Y, Zheng T, Li S* Development of a gene signature associated with iron metabolism in lung adenocarcinoma. Bioengineered. 2021 Dec;12(1):4556-4568. doi: 10.1080/21655979.2021.1954840. PMID: 34323652.3.Qin F, Sun Y, Deng K, Qin J, Xu Z, Wei J, Yuan L, Zheng T, Li S*. Comprehensive analysis of DNA damage repair in squamous cell carcinoma subtypes. Life Sci. 2021 Aug 1;278:119559. doi: 10.1016/j.lfs.2021.119559. Epub 2021 Apr 28. PMID: 33932441.4.Qin F, Lin S, Deng K, Qin J, Xu Z, Yuan L, Wei J, Sun Y, Zheng T, Li S*. Comprehensive analysis of angiogenesis subtype of squamous cell carcinoma. World J Surg Oncol. 2021 Sep 14;19(1):275. doi: 10.1186/s12957-021-02367-3. PMID: 34521431; PMCID: PMC8442455.5.Xu Z, Wei J, Qin F, Sun Y, Xiang W, Yuan L, Qin J, Deng K, Zheng T, Li S*. Hypoxia-associated alternative splicing signature in lung adenocarcinoma. Epigenomics. 2021 Jan;13(1):47-63. doi: 10.2217/epi-2020-0399. Epub 2020 Dec 18. PMID: 33336585.6.Wang Z, Shang J, Li Z, Li H, Zhang C, He K, Li S*, Ju W. PIK3CA Is Regulated by CUX1, Promotes Cell Growth and Metastasis in Bladder Cancer via Activating Epithelial-Mesenchymal Transition. Front Oncol. 2020 Dec 3;10:536072. doi: 10.3389/fonc.2020.536072. PMID: 33344221; PMCID: PMC7744743.7.Qin FL, Xu ZY, Yuan LQ, Li S*. Novel immune subtypes of lung adenocarcinoma identified through bioinformatic analysis[J]. FEBS Open Bio. 2020;10(9):1921-19338.Xu ZY, Zhao M, Chen W, Li S*. Analysis of prognostic genes in the tumor microenvironment of lung adenocarcinoma[J]. PeerJ. 2020;8: e9530.9.Xu Z, Xiang W, Chen W, Li S*. Circ-IGF1R inhibits cell invasion and migration in non-small cell lung cancer[J]. Thorac Cancer. 2020;11(4):875-887.10.Shang J; Wang Z; Chen W; Yang Z; Zheng L; Wang S; Li S*. Pseudogene CHIAP2 inhibits proliferation and invasion of lung adenocarcinoma cells by means of the WNT pathway. J Cell Physiol. 2019;234(8):13735-13746.11.Shang J, Song Q, Yang Z, Li D, Chen W, Luo L, Wang Y, Li S*. Identification of lung adenocarcinoma specific dysregulated genes with diagnostic and prognostic value across 27 TCGA cancer types. Oncotarget. 2017;8(50):87292-87306.12.Li D, Chen W, Shang J, Luo L, Wang Y, Shang J, Zhang Y, Chen G, Li S*. Prospective lncRNA-miRNA-mRNA regulatory network of long non-coding RNA LINC00968 in non-small cell lung cancer A549 cells: A miRNA microarray and bioinformatics investigation. Int J Mol Med. 2017;40(6):1895-1906.13.Chen W, Tang R, He R, Li D, Liang L, Zeng J, Hu X, Ma J, Li S* and Chen G. Clinical roles of the aberrantly expressed lncRNAs in lung squamous cell carcinoma: a study based on RNA-sequencing and microarray data mining. Oncotarget. 2017;8(37):61282-61304.14.Zhang J-y, Shang J, Huo T-m, Zhang B, Chen G, Zeng Z-y and Li S-k*. Local application of paeonol prevents early restenosis: a study with a rabbit vein graft model. Journal of Surgical Research. 2017; 212:278-287.
擅长
熟练应用当前最先进的微创技术进行胸外科手术。精通胸外科各种常规及复杂手术的技巧。对各种普胸（肺、食管、纵隔）外科疾病的诊断与治疗有丰富的临床经验和深厚的造诣。手术切除胸部恶性肿瘤（肺癌、食管癌等）干净彻底。实施以病人为中心的个体化精准诊疗。临床诊疗严谨慎密，外科技术细腻精致。经常受邀到广西各地会诊、讲学并指导胸外科疾病诊治，治疗效果获得患者广泛好评。
